Guidance on Key Considerations for the Identification and Selection of Safer Chemical Alternatives

This guide provides a general approach and criteria for the selection of alternatives, focusing on minimum assessment criteria and recommended assessment practices for four core areas of alternatives evaluations:

• determining the assessment’s scope
• comparative hazard assessment
• comparative exposure assessment
• integration of hazard and exposure results to select a safer alternative.

The guidance also includes recommendations for moving beyond the minimum criteria and assessment practices.