US EPA 2011: Design for the Environment Program Alternatives - Assessment Criteria for Hazard Evaluation

To ensure that the Alternatives Assessment Criteria for Hazard Evaluation remain relevant and useful for distinguishing among chemicals, DfE may update the criteria based on experience conducting alternatives assessments and on stakeholder input. Additional developments likely to prompt criteria review, reevaluation, and possible revision include changes to the Globally Harmonized System (GHS) or EPA programmatic criteria, which are integral to the Alternatives Assessment Criteria, as well as advances in science, such as those relating to endpoint characterization or testing methodologies.